ImmunoGuide® Enzyme immunoassay (ELISA) test kit for the determination of free antibodies directed against the drug Adalimumab (Humira®) in serum and plasma.<br><br>
The drug Adalimumab (trade name Humira®) is a recombinant human IgG1 monoclonal antibody specific for human tumor necrosis factor alpha (TNF-α). Adalimumab was created using phage display technology resulting in an antibody with human derived heavy and light chain variable regions and human IgG1:ƙ constant regions. Adalimumab is used to treat auto-immune disorders. One of the major concerns, despite of its wide usage, is the potential development of anti drug antibody (ADA) which in turn may interfere with the drug efficacy as mainly judged by observing the relapse of signs and symptoms of disease and necessitate dose-escalation or potentially ending up the treatment.<br><br>
The ImmunoGuide Antibody to Adalimumab ELISA kit has been designed for the measurement of free antibodies against this drug. It does not detect such antibodies which already are bound to the drug. For research use only, not for use in diagnostic procedures.
- Assay Description:
- 1 hour incubation (RT) + 1 hour (RT) + 15 min. (RT) = 2 hours, 20 min. total incubation time
- Catalog number:
- TM09009
- configuration:
- 96 Determinations, 12x8 removable strips
- controls:
- Positive control
- design:
- Enzyme immunoassay (ELISA) technique
- FDA Status:
- For research use only, not for use in diagnostic procedures
- MSDS:
- Available upon request
- notes:
- The protocol for this product (see above) is intended to serve as an example only. Please refer to the Instructions For Use provided with the assay kit for precise details.
- Protocol:
- Sample types:
- Serum and plasma
- Sample volume:
- 10 µL
- Standards:
- 5 Standards, ready to use
- Standard range:
- 0 / 5 - 150 ng/mL
- Storage:
- 2 - 8 °C
- Sensitivity:
- 5 ng/mL
- Species:
- Human
- Products related:
- Adalimumab (Humira®) ELISA
- Additional info:
