Amyloid Beta / APP Research Kits & Antibodies

Alzheimer's disease is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NTFs) in the brain.

Amyloid Beta is a peptide derived from the amyloid precursor protein (APP), which is cleaved by beta secretase and gamma secretase to yield Aβ. Aβ is the main component of Amyloid plaques, which are insoluble clumps of beta proteins that are potentially toxic to neurons and their synapses.

Research suggests that the plaques disrupt communication between brain cells, which would result in cognitive decline.

The Tau protein is a microtubule-associated protein which stabilizes the microtubules that transport intracellular substances in nerve cells. When Tau malfunctions, it detaches from these microtubules and sticks to other Tau molecules, where threads are formed. These threads eventually result in neurofibrillary tangle.

Since Tau is interfering with intraneuronal transport and metabolism during this process, research suggests this plays another major role in cognitive decline.

In addition to a complete selection of research assays for the various Amyloid beta molecules, IBL-America also offers antibodies and test kits targeting Tau protein, APPα and β, as well as other significant molecules.

Amyloid Beta (1-42) (Mouse/Rat) Aβ

Solid phase sandwich ELISA for the determination of Mouse/Rat Amyloid Beta ( 1-42 ) Aβ in serum or EDTA plasma. For research use only, not for use in diagnostic procedures. The first case of Alzheimer's disease was defined and...

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Amyloid Beta (1-42) Aβ

Solid phase sandwich ELISA for the determination of human Aβ ( 1-42 ) in cerebrospinal fluid, cell culture media or the extract from brain tissue. For research use only, not for use in diagnostic procedures. The first case of...

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Amyloid Beta (1-43) (FL) Aβ

Solid phase sandwich ELISA for the determination of human Amyloid Beta (1-43) Aβ in cerebrospinal fluid, brain extract of Tg mouse and cell culture supernatant. For research use only, not for use in diagnostic procedures. The...

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Amyloid Beta (1-x) Aβ

Solid phase sandwich ELISA for the determination of human Aβ (1-x) in EDTA-plasma, cerebrospinal fluids, serum, cell culture media or the extract from brain tissue. For research use only, not for use in diagnostic procedures...

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Amyloid Beta (82E1-specific) Aβ Oligomers

Solid phase sandwich ELISA for the determination of human Aβ molecules which bind to anti-human Aβ (N) (82E1) mouse MoAb with two or more epitopes (oligomers, polymers with a protein etc.) in serum, EDTA-plasma and brain tissue extract. For...

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Amyloid Beta (N) (82E1) Aβ Anti-Human Mouse IgG MoAb

Alzheimer's disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid (Aβ) peptide, a 40 to 43 amino acid...

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Amyloid Beta (N) (82E1) Aβ Anti-Human Mouse IgG MoAb Biotin

Alzheimer's disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid (Aβ) peptide, a 40 to 43 amino acid...

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Amyloid Beta (N) Aβ Anti-Human Rabbit IgG Affinity Purify

Alzheimer's disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid (Aβ) peptide, a 40 to 43 amino acid...

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Amyloid Beta (N3pE) (8E1) Aβ Anti-Human Mouse IgG MoAb

The first case of Alzheimer's disease (AD) was reported by Dr. A. Alzheimer, the German neuropathologist in 1907. The plaques which appear in the brains of AD patients mostly consist of Amyloidβ protein and it has been considered as...

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Amyloid Beta (N3pE) Aβ

Solid phase sandwich ELISA for the determination of Human Amyloid Beta (N3pE-42) Aβ in brain tissue extract. For research use only, not for use in diagnostic procedures. The first case of Alzheimer's disease was defined and...

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Amyloid Beta (N3pE-40) Aβ

Solid phase sandwich ELISA for the determination of Human Aβ (N3pE-40) in brain tissue extract. For research use only, not for use in diagnostic procedures. The first case of Alzheimer's disease was defined and reported in 1907...

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Amyloid Beta E22P ( 11A1 ) Aβ Anti-Human Mouse IgG MoAb

Alzheimer’s disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. Aggregation of the 42-mer amyloid β-protein (Aβ42) plays a critical role in the pathogenesis...

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