Rapamycin is a lipophilic macrolide compound and induces a G1 phase growth arrest in S. cerevisiae and mammalian cells. The mammalian target of rapamycin (mTOR) has a molecular weight of 290 kDa and a Ser/Thr protein kinase activity. mTOR has been shown to be an upstream regulator of translational effectors, such as p70 S6 kinase and eIF4E- binding protein 1, and plays a crucial role in a nutrient-sensitive signaling pathway that regulates cell growth. For research use only, not for use in diagnostic procedures.
- application:
- WB, IP
- Catalog number:
- 10343
- clone:
- N5D11
- concentration:
- Please see datasheet
- Datasheet:
- formulation:
- Lyophilized product from 1% BSA in PBS containing 0.05% NaN3
- immunogen:
- Recombinant Rat mTOR
- isotype:
- IgG1
- MSDS:
- notes:
- For research use only, not for use in diagnostic procedures.
The datasheet for this product (see above) is intended to serve as an example only. Please refer to the datasheet provided with the antibody for precise details. - Other names:
- Please see datasheet
- Protocol:
- size:
- 100 µg
- storage:
- Lyophilized product, 5 years at 2 - 8 °C; Solution, 2 years at -20 °C
- Species:
- Rat
- Host:
- Mouse
