The poly ADP-ribosylation is one of post translational modification of proteins, and is the addition of many ADP-ribose moieties to a protein. This protein modification is carried out by the poly ADP-ribose polymerases (PARPs), which are found in most eukaryotes, but not prokaryotes or yeast. The reaction is involved in various cellular processes and conditions, including DNA repair, transcriptional control, genomic stability, cell death and transformation, and several reports have been indicated in relation to cancer and autoimmune disease. This antibody reacts specifically to poly ADP-ribose (PAR). For research use only, not for use in diagnostic procedures.
- application:
- IHC, WB, ICC
- Catalog number:
- 10407
- clone:
- 10H
- concentration:
- Please see datasheet
- Datasheet:
- formulation:
- Lyophilized product from PBS containing 1% BSA and 0.05% NaN3
- immunogen:
- Purified Poly (ADP-ribose)
- isotype:
- IgG3, κ
- MSDS:
- notes:
- For research use only, not for use in diagnostic procedures.
The datasheet for this product (see above) is intended to serve as an example only. Please refer to the datasheet provided with the antibody for precise details. - Other names:
- Please see datasheet
- Protocol:
- size:
- 100 µg
- storage:
- Lyophilized product, 5 years at 2 - 8 °C; Solution, 2 years at -20 °C
- Host:
- Mouse
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