RET finger protein (RFP) belongs to the large B-box RING finger protein family and is known to become oncogenic by fusion with RET tyrosine kinase. Although RFP is reported to be a nuclear protein that is present in the nuclear matrix, its function is largely unknown. RFP interacts with Enhancer of Polycomb (EPC) and strongly represses the gene transcription. Yeast two-hybrid assays revealed that the coiled-coil domain of RFP was associated with the EPcA domain and the carboxyl-terminal region of EPC. RFP may be involved in the epigenetic gene silencing mechanism cooperating with Polycomb group protein. For research use only, not for use in diagnostic procedures.
- application:
- WB, IHC, IP, ICC
- Catalog number:
- 18791-S
- Datasheet:
- formulation:
- Lyophilized product from 1% BSA in PBS containing 0.05% NaN3
- immunogen:
- Synthetic peptide for C-terminal portion (IDGFSGHVGNHGHSMETSP) of RFP
- MSDS:
- notes:
- For research use only, not for use in diagnostic procedures.
The datasheet for this product (see above) is intended to serve as an example only. Please refer to the datasheet provided with the antibody for precise details. - Other names:
- Please see datasheet
- Protocol:
- purification:
- Affinity Purified with synthetic peptide
- size:
- 10 µg
- specificity:
- The antigen peptides is selected a common region between human and mouse
- storage:
- Lyophilized product, 5 years at 2 - 8 °C, Solution, 2 years at -20 °C
- Host:
- Rabbit
- References:
