Titin (connectin) is a protein that consists of 34,350 amino-acid and specifically expresses in a cross-striated muscle. The molecular weight of human titin is 3,816 kDa and it has been known that as the largest protein among of existing proteins in a living body. It is one of sarcomere structured protein that is a minimum unit of myofibrillary protein and it has a role as an elastic protein for recovering the length of shortened sarcomere by its contraction. It has been known that titin is cleaved by proteolytic enzymes such as calpain and matrix metalloprotease if muscles are damaged. Titin N-Fragment, one of these fragments, is 26kDa N-terminus fragments which is excreted into the urine. It has been researched in the field of muscular dystrophy, sports medicine, cardiac disease, NAFLD, sarcopenia and frailty and it is considered as a molecule reflects status of muscles. This antibody can be used for ELISA to detect human urinary Titin N-Fragment. For research use only, not for use in diagnostic procedures.
- application:
- ELISA
- Catalog number:
- 10425
- Datasheet:
- clone:
- 144A2
- concentration:
- 1 mg/ml after reconstitution with 0.1 ml H2O
- formulation:
- Lyophilized product from in Dulbecco's-PBS
- immunogen:
- Recombinant Titin (1-200)
- isotype:
- IgG2b
- notes:
- For research use only, not for use in diagnostic procedures.
The datasheet for this product (see above) is intended to serve as an example only. Please refer to the datasheet provided with the antibody for precise details. - size:
- 100 µg
- storage:
- 2 - 8 °C
- Species:
- Mouse
- Additional Info:
