Antibodies

An antibody is an immunoglobulin protein capable of specific combination with an antigen/hapten that has elicited and induced an immune response. Antibodies are produced by B cells in response to presence of antigen/hapten.

mLST8 (L17) Anti-Human Rabbit IgG Affinity Purify 1

mLST8 (mammalian lethal with sec-13), an about 39 kDa protein which has WD40 domains, has been identified as a configuration factor of mTORC1/mTOR complex 1 and then found to be also a configuration factor of mTORC2. mLST8 is conserved over species and...

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MBD2 (Methyl-CpG-Binding Protein 2) Anti-Human Rabbit IgG Affinity Purify 1

Methylation at CpG dinucleotides in genomic DNA is a fundamental epigenetic mechanism of gene expression control in vertebrates. Proteins with a methyl-CpG binding domain (MBD) can bind to single methylated CpGs and most of them are involved in...

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LRRK2 Anti-Human Rabbit IgG Affinity Purify 1

Parkinson’s disease is one of the most common neurodegenerative disease and characterized by progressive loss of dopaminergic neurons. Leucine-rich repeat kinase 2 (LRRK2) is one of the responsible gene of autosomal dominant Parkinson’s...

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LRG (329) Anti-Human Rabbit IgG Affinity Purify 1

Among the diseases which should be distinguished from iNPH (idiopathic normal pressure hydrocephalus) of elderly people showing symptoms such as gait disorder and dementia, there are some neurodegenerative diseases such as Alzheimer's disease, FTLD...

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LRG (128) Anti-Rat Rabbit Affinity Purify 1

Among the diseases which should be distinguished from iNPH (idiopathic normal pressure hydrocephalus) of elderly people showing symptoms such as gait disorder and dementia, there are some neurodegenerative diseases such as Alzheimer's disease, FTLD...

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FGFR2/K-sam Anti-Human Rabbit IgG Affinity Purify 1

The K-sam (KATO-III cells-derived stomach cancer amplified gene) gene was originally cloned from KATO-III cells, human gastric cancer, as an amplified gene. And it is identical to FGFR2 (fibroblast growth factor receptor 2), bek (bacteria-expressed...

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KDR (C) Anti-Human Rabbit IgG Affinity Purify 1

KDR, alternative name Flk-1 (type 2 receptor), is one of the receptors for VEGFs, important growth factors for vasculo-genesis, angiogenesis and lymphangio-genesis. Flt-1 (type 1 receptor) is also known as a VEGF receptor. In particular, it is believed...

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KC Anti-Mouse Rabbit IgG 1

GRO (Growth Related Oncogene) belonging to IL-8 family is polypeptide which has three isoforms α, β and γ, and it inhibits proliferation of endothelial cells. GRO/CINC-1 (cytokine-induced neutrophil chemo attractant 1) was originally...

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KC (N) Anti-Mouse Rabbit IgG Affinity Purify 1

Mouse KC (Keratinocyto-derived Cytokine) is a counterpart of Human GRO protein. It is reported that KC is produced in such as activated monocyte and fibroblast.

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JAB/SOCS-1 (J192) Anti-Human Rabbit IgG Affinity Purify 1

The Janus family of protein tyrosine kinases (JAKs) and STAT transcription factors regulate cellular processes involved in cell growth, differentiation, and transformation through their association with cytokine receptors. The CIS family of proteins...

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IRF-3 Anti-Human Rabbit IgG Affinity Purify 1

Interferon Regulatory Factor-3 (IRF-3) is the gene coding for a regulatory factor that mediates the action of IL-1, TNFα and LPS. It is reported that IRF-3 controls the production of interferons and chemokines in virus infected cells, by a...

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IL-6 (N) Anti-Rat Rabbit IgG Affinity Purify 1

Interleukin-6 (IL-6) is one of cytokines which was found as a B cell differentiation-inducing factor. In these days, IL-6 is generating a lot of attention not only from antibody-producing system but also from assorted physiologically activity such as...

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