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Rituximab (Rituxan®) (mAb-based)

$1,110.00
SKU:
TM09016
Bulk Pricing:
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ImmunoGuide® Enzyme immunoassay (ELISA) test kit for the determination of free Rituximab (Mabthera®, Rituxan®) in serum and plasma.<br><br>

The drug Rituximab (trade name Rituxan® and Mabthera®) is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is a glycosylated IgG1 kappa immunoglobulin containing murine light-and heavy-chain variable region sequences (Fab domain) and human constant region sequences (Fc domain). Rituximab is composed of 1,328 amino acids and has an approximate molecular weight of 144 kD. Rituximab has a high binding affinity for the CD20 antigen.<br><br>

The specificity of this test system is achieved by using a monoclonal antibody (clon 9D5b) for the coating of the microtiter plate. This antibody is specific for Rituximab only (regardless whether Rituxan® and Mabthera®) and does not cross react with other CD20 catchers. For research use only, not for use in diagnostic procedures.

Assay Description:
1 hour incubation (RT) + 30 min. (RT) + 10 min. (RT) = 1 hour, 40 min. total incubation time
Catalog number:
TM09016
configuration:
96 Determinations, 12x8 removable strips
controls:
None provided
design:
Enzyme immunoassay (ELISA) technique
FDA Status:
For research use only, not for use in diagnostic procedures
MSDS:
Available upon request
notes:
The protocol for this product (see above) is intended to serve as an example only. Please refer to the Instructions For Use provided with the assay kit for precise details.
Other names:
Mabthera®, Rituxan®
Protocol:

Protocol

Sample types:
Serum and plasma
Sample volume:
10 µL
standards:
5 standards, concentrated
Standard range:
0 / 6.0 - 200.0 ng/mL
storage:
2 - 8 °C
sensitivity:
2 ng/mL
Species:
Human
Products related:
Anti-Rituximab (Rituxan®) ELISA
Additional info:

Pamphlet