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Trastuzumab (Herceptin®)

$1,110.00
SKU:
TM09013
Bulk Pricing:
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Immunoguide® Enzyme immunoassay (ELISA) test kit for the determination of free Trastuzumab (Herceptin®, Herclon®) in serum and plasma.<br><br>

Trastuzumab (trade name Herceptin®, Herclon®) is a recombinant DNA-derived humanized monoclonal antibody that selectively targets the extracellular domain of the human epidermal growth factor receptor 2 protein (HER2). The antibody is an IgG1 kappa that contains human framework regions with the complementarity-determining regions of a murine anti p185 HER2 antibody that binds to HER2. Trastuzumab blood concentrations throughout the dosing interval expected to be remaining above those considered necessary for anticancer activity.<br><br>

In this context, identification of biomarkers for (non-)response and risk factors for adverse drug reactions that might be related to serum concentrations and maintaining the effective concentration of Trastuzumab in order to potentially avoid some side effects with a reliable method might be beneficial. For research use only, not for use in diagnostic procedures.

Assay Description:
60 min. incubation (RT) + 30 min. (RT) + 20 min. (RT) = 1 hour, 50 min. total incubation time
Catalog number:
TM09013
configuration:
96 Determinations, 12x8 removable strips
controls:
None provided
design:
Enzyme immunoassay (ELISA) technique
FDA Status:
For research use only, not for use in diagnostic procedures
MSDS:
Available upon request
notes:
The protocol for this product (see above) is intended to serve as an example only. Please refer to the Instructions For Use provided with the assay kit for precise details.
Protocol:

Protocol

Sample types:
Serum and plasma
Sample volume:
10 µL
standards:
5 standards, ready to use
Standard range:
0 / 6 - 200 ng/mL
storage:
2 - 8 °C
sensitivity:
5 ng/mL
Species:
Human
Products related:
Anti-Trastuzumab (Herceptin®) ELISA
Trastuzumab (Herceptin®) (mAb-based) ELISA
Additional info:

Pamphlet