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Background The complement system plays an essential role in chronic, autoimmune and infectious disease. There are three pathways of complement activation, namely the classical, the alternativ … read more

Researchers at University of California, San Francisco (UCSF) are taking an innovative approach to battling neurodegenerative diseases like Alzheimer’s disease and dementia. Rather than trying to u … read more

Monocyte activation detected prior to a diagnosis of schizophrenia in the US Military New Onset Psychosis Project (MNOPP) Low-grade inflammation is present in some cases of schizophrenia, particu … read more

Distinct spatiotemporal accumulation of N-truncated and full-length amyloid-β42 in Alzheimer’s disease Accumulation of amyloid-β peptides is a dominant feature in the pathogenesis of Alzheime … read more

α-Synuclein is a 14.5kDa, soluble form protein which consists of 140 amino-acid residue and it is known as an intrinsically disordered protein. It is mainly expressed in cerebral neocortex, hippo … read more