New Titin N-Fragment Antibodies!
May 27th 2020
We are pleased to announce two new Titin monoclonal antibodies: Anti-Titin-N (144A2) Mouse IgG and Anti-Titin-N (53A1) Mouse IgG.
Titin (connectin) is a protein that consists of 34,350 amino-acids and specifically expresses in a cross-striated muscle. The molecular weight of human titin is 3,816 kDa and is the largest protein (among existing proteins) in the living body. It is a sarcomere protein that has a role as an elastic protein for recovering the length of shortened sarcomeres by its contraction. It is known that titin is cleaved by proteolytic enzymes such as calpain and matrix metalloprotease if muscles are damaged. A fragment of Titin, Titin N-Fragment, is a 26kDa N-terminus fragment that is excreted into the urine. It has been researched in the field of muscular dystrophy, sports medicine, cardiac disease, NAFLD, sarcopenia and frailty and it is considered as a molecule reflects status of muscles.
These antibodies specifically react to human Titin N-Fragment and can be used for ELISA application. Contact us or click the product page links below for more information.