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Product Re-Launch: 3-Methoxytyramine (3-MT) RIA

Sep 30th 2019

It’s with pleasure to inform you that the revision of the 3-MT-RIA (Catalog number IB88528) is finished and that this assay is available again effective immediately.

This is the FIRST COMMERCIAL IMMUNOASSAY WORLDWIDE for the quantitative determination of 3-MT in human plasma.

BACKGROUND:

The determination of normetanephrine and metanephrine in plasma is a sensitive test for investigating phaechromocytoma and paragangliomas (PPGLs), but it does not provide the possibility to detect dopamine-producing tumors. Dopamine and especially its O-methylated metabolite 3-MT are reliable biomarkers for the detection of malignant PPGLs.

This assay excellently compares to the LC-MS/MS method and offers an accurate, selective and sensitive measurement of 3-MT.

The assay itself uses an elegant extraction procedure followed by a competitive RIA (please refer to the instructions for use).

With this assay we are now able to offer the most comprehensive panel worldwide for the measurement of PPGL / Pheochromocytoma-relevant parameters including the assays for:

  • Urinary Metanephrine / Normetanephrine (ELISA & RIA)
  • Plasma Metanephrine / Normetanephrine (ELISA & RIA)
  • Catecholamines in plasma and urine (ELISA & RIA)
  • Chromogranin A (ELISA)
  • and – closing the gap – 3-Methoxytyramine (RIA)
Catalog NumberIB88528
Controls2 controls, ready to use.
Sample TypesPlasma
Sample Volume750 µL
Standards6 standards, ready to use.
Standard Range0 / 2 - 150 pg/mL
Sensitivity1.10 pg/mL
Incubation TimeOvernight + 4 hours total incubation time
FDA StatusResearch Use Only