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C-ERC/Mesothelin (306) Anti-Rat Rabbit Igg Affinity Purify

$550.00
SKU:
28001
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Erc has been identified as a gene showing stronger expression in cancer-affected renal cell than in normal renal tissue in Eker rats (a rat model of renal cancer). The human homologue of the protein encoded by this gene is called MPF (megakaryocyte potentiating factor) or mesothelin. This protein is detected especially prominently in mesothelial cells, and its involvement has been suggested in the development of mesothelioma, making it a promising tumor marker. In humans, involvement of this protein has also been suggested in the development of pancreatic, ovarian and pulmonary cancers, etc. The protein is expressed as a GPI anchor-type membranous protein (about 71 kDa in molecular weight), which is thought to be digested by a furin-like protease to yield fragments about 31 kDa and 40 kDa in size. We have prepared an antibody specific to C-ERC/Mesothelin (40 kDa fragment). This antibody specifically recognizes rat C-ERC/Mesothelin which is applicable for the analysis of ERC expression in mesothelial cells, tumors, cell lines, etc. For research use only, not for use in diagnostic procedures.

application:
IHC, WB
Catalog number:
28001
Datasheet:

Click for Datasheet

formulation:
Lyophilized product from 1% BSA in PBS containing 0.05% NaN3
immunogen:
Synthetic peptide of the part of Rat C-ERC/Mesothelin (GKEPNVVDENLIFYQNWELEA)
MSDS:

Click for MSDS

notes:
For research use only, not for use in diagnostic procedures.
The datasheet for this product (see above) is intended to serve as an example only. Please refer to the datasheet provided with the antibody for precise details.
Other names:
Please see datasheet
Protocol:

Click for Antibody Protocol

purification:
Purified with antigen peptide
size:
100 µg
specificity:
Please see datasheet
storage:
Lyophilized product, 5 years at 2 - 8 °C; Solution, 2 years at -20 °C.
Species:
Rat
Host:
Rabbit
References:

Click for References