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CD109 (11H3) Anti-Human Mouse IgG MoAb 1
CD109 is a glycosyl-phosphatidyl-inositol (GPI) - anchored glycoprotein about 180 - 190 kDa. It is shown that CD109 is expressed in vascular endothelial cells, some epithelial cells, activated T-cells and platelets, and subset of CD34+ megakaryocytic...
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NP95 (mt40) Anti-Human Mouse IgG MoAb 1
Np95 has been originally found as a tumor-specific nuclear antigen of 95kDa in mice. Experiments using B10 strains showed that Np95 is enriched in precancerous cells and is abnormally expressed throughout cell cycle in radiation-induced lymphomatoid...
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Reticulocalbin-1 (TMU-6A1) Anti-Human Mouse IgG MoAb 1
Human Reticulocalbin-1 is a 44kDa protein and belongs to the EF (elongation factor) -hand calcium-binding protein family, and it is known as a luminal protein of endoplasmic reticulum (ER) with the C-terminal HDEL (ER retention signal) sequence. Although...
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Tie-1 (9C1) Anti-Human Mouse IgG MoAb 1
TIE is a new receptor-type tyrosine kinase that was cloned from K562, a chronic myelocytic leukemia cell line. Its molecular weight is 117 kDa and its structure begins with an immunoglobulin-like domain from the extracellular N terminal, continues to 3...
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PDGFRβ (22B1) Anti-Human Mouse IgG MoAb 1
PDGF, a ligand of PDGFR, has 4 isofoms, A-, B-, C- and D-chains, and forms hetero and/or homo dimers, PDGF-AA, -AB, -BB, -CC, -DD. On the other hand, PDGFR has 2 isoforms, α- and β-chains and forms hetero and/or homo dimers,...
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KDR (23B31) Anti-Human Mouse IgG MoAb 1
KDR, alternative name Flk-1 (type 2 receptor), is one of the receptors for VEGFs, important growth factors for vasculogenesis, angiogenesis and lymphangiogenesis. Flt-1 (type 1 receptor) is also known as a VEGF receptor. In particular, it is believed...
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RIG-I (CTD) Anti-Human Rabbit IgG Affinity Purify 1
RIG-I (retinoic acid inducible gene-I) is one of cytoplasmic viral sencers which has a RNA helicase domain and it is believed to recognize virus-derived double-stranded RNA (dsRNA). It is considered that RIG-I normally exist as inactive form in cytoplasm...
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CD20 (N) (4-6H:2C) Anti-Human Mouse IgG MoAb 1
Rituximab used for treatment of lymphoma is an antibody drug of which target is pan-B cell marker, CD20. It has been reported that the C-terminal region of CD20 undertakes a critical role in a binding to rituximab and the association between C-terminal...
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c-MPL/TPOR (AMM2) Anti-Mouse Rat IgG MoAb 1
Thrombopoietin promotes the growth and differentiation (proliferation) of megakaryocytes which produce platelets. TPOR (Thrombopoietin receptor), which is also called c-MPL (Myeloproliferative leukemia protein) or CD110, is a receptor for thrombopoietin...
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Amyloid Beta E22P ( 11A1 ) Aβ Anti-Human Mouse IgG MoAb 1
Alzheimer’s disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. Aggregation of the 42-mer amyloid β-protein (Aβ42) plays a critical role in the pathogenesis...
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BEC12 (LA5) Anti-Mouse Mouse IgG MoAb 1
Recent years, specific antigens of vascular endothelium have been found one after another, and they contribute to progress of vascular biology. This antibody, being unlike any other prior antibodies, reacts especially with arterial microcirculating...
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LEC26 (LA102) Anti-Mouse Rat IgG MoAb 1
Recent years, LYVE-1 (1999, Banerji et al.), podoplanin (1999, Breiteneder-Geleff et al.) and Prox-1 (1999, Wifle & Oliver) were found one after another as specific antigens of lymphatic endothelium and the approach to lymphatic study has progressed...
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