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p16 INK4a (1H4) Anti-Human Mouse IgG MoAb 1
p16INK4a is a cyclin-dependent kinase (CDK) inhibitor, and binds CDK4 and CDK6 and inhibits their kinase activity. It is also called MTS1 and INK4a, and p15INK4b (MTS2), p18INK4c and p19INK4d are other members of the INK4 family. p16INK4a is a tumor...
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Tau (Phosphorylated) (C5) Anti-Human Mouse IgG MoAb 1
Tau protein is a microtubule-associated protein expressed in neuroaxon and has molecular weight of 50 - 70 kDa. Some Alzheimer's patients have sites where tau protein is accumulated abnormally. This antibody reacts with phosphorylated part in amino acid...
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Anti-TP (ATYMPMAB) Mouse IgG MoAb 1
Thymidylate synthase/TS (EC 2.1.1.45), Dihydropyrimidine dehydrogenase/DPD (EC 1.3.1.2), Thymidine phosphorylase/TP (EC 2.4.2.4) and Orotate phosphoribosyl transferase/OPRT (EC 2.4.2.10) are known as key enzymes related to nucleic-acid metabolism within...
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CD109 (11H3) Anti-Human Mouse IgG MoAb 1
CD109 is a glycosyl-phosphatidyl-inositol (GPI) - anchored glycoprotein about 180 - 190 kDa. It is shown that CD109 is expressed in vascular endothelial cells, some epithelial cells, activated T-cells and platelets, and subset of CD34+ megakaryocytic...
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NP95 (mt40) Anti-Human Mouse IgG MoAb 1
Np95 has been originally found as a tumor-specific nuclear antigen of 95kDa in mice. Experiments using B10 strains showed that Np95 is enriched in precancerous cells and is abnormally expressed throughout cell cycle in radiation-induced lymphomatoid...
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Reticulocalbin-1 (TMU-6A1) Anti-Human Mouse IgG MoAb 1
Human Reticulocalbin-1 is a 44kDa protein and belongs to the EF (elongation factor) -hand calcium-binding protein family, and it is known as a luminal protein of endoplasmic reticulum (ER) with the C-terminal HDEL (ER retention signal) sequence. Although...
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Tie-1 (9C1) Anti-Human Mouse IgG MoAb 1
TIE is a new receptor-type tyrosine kinase that was cloned from K562, a chronic myelocytic leukemia cell line. Its molecular weight is 117 kDa and its structure begins with an immunoglobulin-like domain from the extracellular N terminal, continues to 3...
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PDGFRβ (22B1) Anti-Human Mouse IgG MoAb 1
PDGF, a ligand of PDGFR, has 4 isofoms, A-, B-, C- and D-chains, and forms hetero and/or homo dimers, PDGF-AA, -AB, -BB, -CC, -DD. On the other hand, PDGFR has 2 isoforms, α- and β-chains and forms hetero and/or homo dimers,...
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KDR (23B31) Anti-Human Mouse IgG MoAb 1
KDR, alternative name Flk-1 (type 2 receptor), is one of the receptors for VEGFs, important growth factors for vasculogenesis, angiogenesis and lymphangiogenesis. Flt-1 (type 1 receptor) is also known as a VEGF receptor. In particular, it is believed...
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RIG-I (CTD) Anti-Human Rabbit IgG Affinity Purify 1
RIG-I (retinoic acid inducible gene-I) is one of cytoplasmic viral sencers which has a RNA helicase domain and it is believed to recognize virus-derived double-stranded RNA (dsRNA). It is considered that RIG-I normally exist as inactive form in cytoplasm...
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CD20 (N) (4-6H:2C) Anti-Human Mouse IgG MoAb 1
Rituximab used for treatment of lymphoma is an antibody drug of which target is pan-B cell marker, CD20. It has been reported that the C-terminal region of CD20 undertakes a critical role in a binding to rituximab and the association between C-terminal...
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c-MPL/TPOR (AMM2) Anti-Mouse Rat IgG MoAb 1
Thrombopoietin promotes the growth and differentiation (proliferation) of megakaryocytes which produce platelets. TPOR (Thrombopoietin receptor), which is also called c-MPL (Myeloproliferative leukemia protein) or CD110, is a receptor for thrombopoietin...
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