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Tob (Phosphorylated) Anti-Human Rabbit IgG Affinity Purify
Tob (Transducing molecule of c-ErbB-2) was identified as a molecule that binds tothe receptor tyrosine kinase c-ErbB2 in 1996.After that, Tob2, BTG1, PC3/TIS21/BTG2, ANA, PC3B etc were found as proteins with a homologous region at about 110 amino acids...
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TNF-α Anti-Rat Rabbit IgG Affinity Purify
TNF-α (Tumor Necrosis Factor alpha) is a 17.5 kDa, 157 amino acid protein that is a potent lymphoid factor, which exerts cytotoxic effects on a wide range of tumor cells and other target cells. TNF-α has been suggested to play a...
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TIMP-1 (T172) Anti-Human Rabbit IgG Affinity Purify
Tissue inhibitor of Metalloprotinase 1 (TIMP-1) is endogenous-specific inhibitor produced simultaneously with matrix metalloproteinase (MMP). TIMP-1 inhibits both active MMP to control degeneration of extracellular matrix (ECM) and conversion of...
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Tie (N1125) Anti-Human Rabbit IgG Affinity Purify
TIE is a new receptor-type tyrosine kinase that was cloned from K562, a chronic myelocytic leukemia cell line. Its molecular weight is 117 kDa and its structure begins with an immunoglobulin-like domain from the extracellular N terminal, continues to 3...
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Thioredoxin (C) Anti-Human Rabbit IgG Affinity Purify
Thioredoxin is a 12kDa oxidoreductase enzyme containing a dithiol-disulfide active site, and it acts as antioxidants by facilitating the reduction of other proteins by cysteine thiol-disulfide exchange. This redox-regulatory protein thioredoxin has...
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Tau Anti-Human Rabbit IgG Affinity Purify
Tau protein is a microtubule-associated protein expressed in neuroaxon and has molecular weight of 50-70 kDa. Some Alzheimer's patients have sites where tau protein is accumulated abnormally. It is known that six isoforms of tau protein formed by...
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α-Synuclein (S122) Anti-Human Rabbit IgG Affinity Purify
The pre-synaptic protein, α-synuclein, has been associated with the pathogenesis of several neurodegenerative diseases. These include prevalent conditions such as Parkinson's disease (PD), dementia with Lewy bodies (DLB), and the Lewy body variant...
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Syndecan-4 Anti-Human Rabbit IgG Affinity Purify
Syndecan, a cell surface proteoglycan, is an integral membrane protein acting as a receptor for the extracellular matrix. The syndecan family of four transmembrane heparan sulfate proteoglycans binds a variety of soluble and insoluble extracellular...
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Anti-Synaptotagmin IV Rabbit IgG Affinity Purify
Synaptotagmin family proteins consist of a single N-terminal transmembrane domain and C-terminal tandem C2 domains (C2A and C2B), which have the ability to bind Ca2+ and phospholipid, and 15 synaptotagmin isoforms have been reported in the mouse and...
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Anti-Smad3L (Ser 208/213 Phosphorylated) Rabbit IgG Affinity Purify
Smads are critical mediators conveying signals from the TGF-β-superfamily members to the nucleus. Activated TGF-β type I receptor (TβRI) and c-Jun N-terminal kinase (JNK) differentially phosphorylate Smad3 to convert two distinctive...
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Anti-Smad3C (Ser 423/425 Phosphorylated) Rabbit IgG Affinity Purify
Smads are critical mediators conveying signals from the TGF-β-superfamily members to the nucleus. Activated TGF-β type I receptor (TβRI) and c-Jun N-terminal kinase (JNK) differentially phosphorylate Smad3 to convert two distinctive...
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Sir2/SIRT1 Anti-Human Rabbit IgG Affinity Purify
Imai et al. have found that S. cerevisiae Sir2p and its higher eukaryotic orthologs are novel nicotinamide adenine dinucleotide (NAD)-dependent histone/protein deacetylases. Sir2 proteins promote longevity in yeast and in C. elegans by silencing rDNA and...
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