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Claudin-12 (C) Anti-Mouse Rabbit IgG Affinity Purify 1

$132.00
SKU:
18801-S
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Claudin is a transmembrane protein that 4 times goes through the membrane to be formed a gene family and a tight junction molecule that is involved in cell to cell adhesion of epithelial and endothelial cell sheets. It also gets together among several different and/or same type of Claudin. The structure consists of 2 loops that are found in extracellular and both its N-terminal and C-terminal domain in intracellular.
Fundamental structures among its family are common and its molecular weight is around 20 - 27kDa. Its C-terminal domain binds PDZ domain of ZO-1, ZO-2 and ZO-3 (protein behind the transmenbrane).
It has been known that Claudin-1, 2, 6, 7 and 15 are distributed in mouse liver and kidneys while Claucin-5 is in vascular endothelium. For research use only, not for use in diagnostic procedures.

application:
WB, IHC, ICC
Catalog number:
18801-S
Datasheet:

Click for Datasheet

formulation:
Lyophilized product from 1% BSA in PBS containing 0.05% NaN3
immunogen:
Synthetic peptide of part of C terminal of Mouse Claudin-12 (GMHTYSQPYSSRSRLSAI)
MSDS:

Click for MSDS

notes:
For research use only, not for use in diagnostic procedures.
The datasheet for this product (see above) is intended to serve as an example only. Please refer to the datasheet provided with the antibody for precise details.
Other names:
Please see datasheet
Protocol:

Click for Antibody Protocol

purification:
Purified with antigen peptide
size:
10 µg
specificity:
Claudin-12 specific. Non-cross-reacts with Claudin-1, -2, -3, -4, -5, -6, -7, -8 and -15
storage:
Lyophilized product, 5 years at 2 - 8 °C, Solution, 2 years at -20 °C
Species:
Mouse
Host:
Rabbit