Enzyme linked immunosorbent assay (ELISA) for the determination of IgM antibody to Cytomegalovirus (CMV) in human serum. For research use only, not for use in diagnostic procedures.<br><br>
Cytomegalovirus (CMV) is a member of the herpes group of viruses. Most adults and children who catch CMV have no symptoms and are not harmed by the virus. CMV infection is of clinical significance primarily in pregnant women, newborn infants with possible congenital infection, immunosuppressed transplant patients and individuals with AIDS. CMV is so prevalent as over 60% of people catch the infection at some time in their lives. Significant increases in CMV IgG antibody by ELISA suggest recent infection or reactivation of a latent CMV infection. CMV IgM antibody can be detected by ELISA in both primary CMV infections (93-100%) and in reactivated infection (40%). An IgM response may be reduced or absent in immunocompromised subjects with active infection. In transplant subjects the CMV infection can be associated with higher morbidity and mortality.
- Assay Description:
- 20 min.incubation (RT) + 20 min. (RT) + 10 min. (RT) = 50 min. total incubation time
- Catalog number:
- IB19206
- configuration:
- 96 Determinations, 12x8 removable strips
- controls:
- Positive and negative controls, ready to use
- design:
- Enzyme linked immunosorbent assay (ELISA) technique
- FDA Status:
- For research use only, not for use in diagnostic procedures
- MSDS:
- notes:
- The protocol for this product (see above) is intended to serve as an example only. Please refer to the Instructions For Use provided with the assay kit for precise details.
- Other names:
- Cytomegalovirus IgM
- Protocol:
- Sample types:
- Human serum
- Sample volume:
- 100 µL properly diluted (1:21) unknown / determination
- standards:
- 1 calibrator, ready to use
- Standard range:
- Results of unknowns compared to cut-off value for interpretation
- storage:
- 2 - 8 °C
- Species:
- Human
