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COX-2 (C631) Anti-Human Rabbit IgG Affinity Purify 1

$132.00
SKU:
18516-S
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COX-1 and COX-2 (Cyclooxygenase 1,2) are also called prostaglandin endoperoxide H synthase, and are important enzymes as catalysts for the reaction in prostaglandin H2 (PGH2) synthesis from the arachidonic acid. COX-1 and COX-2 have the homology of about 60% at the amino acid level. COX-1 is expressed constitutively in many organs such as kidney, stomach, vascular smooth muscle or platelets widely and it is thought to play a so-called housekeeping role. On the other hand, COX-2 cannot be usually detected from organs, however, it is high-level expressed by macrophage and other cells in response to the stimulation such as various cytokines, hormones, the tumor cause medicines, inflammation mediators, or mitogens, therefore, it is thought that COX-2 produces prostaglandin in relation to the inflammation condition. For research use only, not for use in diagnostic procedures.

application:
WB, IHC
Catalog number:
18516-S
Datasheet:

Click for Datasheet

formulation:
Lyophilized product from 1% BSA in PBS containing 0.05% NaN3
immunogen:
Synthetic peptide for a part of Human COX-2
MSDS:

Click for MSDS

notes:
For research use only, not for use in diagnostic procedures.
The datasheet for this product (see above) is intended to serve as an example only. Please refer to the datasheet provided with the antibody for precise details.
Other names:
Please see datasheet
Protocol:

Click for Antibody Protocol

purification:
Affinity Purified with synthetic peptide
size:
10 µg
specificity:
Human COX-2 specific. Non-cross-reacts with Human COX-1 and Rat COX-2.
storage:
Lyophilized product, 5 years at 2 - 8 °C; Solution, 2 years at -20 °C.
Species:
Human
Host:
Rabbit