CyCAP is a binding protein for cyclophilin C in competition with cyclosporine. It is present in brain, kidney and macrophage cells and is known as an inflammation-related protein. In recent years, it has been reported that CyCAP forms complexes with calcineurin and NFATc1 in macrophages and enhances their phagocytosis activity. CyCAP is detected in macrophages both of in vivo and in vitro, and the signals increase when the macrophages are activated. Additionally, it is stained in neurocytes of rat brain tissues. For research use only, not for use in diagnostic procedures.
- application:
- IHC, WB, IP, ICC
- Catalog number:
- 28125
- Datasheet:
- formulation:
- Lyophilized product in PBS containing 1% BSA and 0.05% NaN3
- immunogen:
- Synthetic peptide of a part of Rat CyCAP (LGRAAFGPGKGPIMLDEVEC). The sequence used is 100% identical with Mouse CyCAP.
- MSDS:
- notes:
- For research use only, not for use in diagnostic procedures.
The datasheet for this product (see above) is intended to serve as an example only. Please refer to the datasheet provided with the antibody for precise details. - Other names:
- Please see datasheet
- Protocol:
- purification:
- Purified with antigen peptide
- size:
- 50 µg
- specificity:
- Cross reacts with mouse CyCAP
- storage:
- Lyophilized product, 5 years at 2 - 8 °C; Solution, 2 years at -20 °C.
- Species:
- Rat
- Host:
- Rabbit
