DbpA (DNA Binding protein A) belongs to the Y-box binding protein family that contain a DNA binding domain, called the cold shock domain, of about 80-amino-acid residues. DbpA was identified as the protein binding to the epidermal growth factor receptor enhancer or c-erbB-2 ptomoter. These Y-box binding proteins are reported to have multiple function, such as the regulations of transcription and translation. It was reported that dbpA was a candidate molecule to accelerate the process of the inflammation-induced hepatocarcinogenesis, the association with the advanced stages of hepatocellular carcinoma and its nuclear localization as a marker of poor prognosis. For research use only, not for use in diagnostic procedures.