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Diabetes & Obesity

Diabetes & Obesity

Diabetes Mellitus is a metabolic syndrome that refers to a group of diseases that affect how the body uses blood sugar (glucose).

Diabetes occurs when the body does not produce sufficient levels of, or correctly respond to, insulin. Insulin is an essential physiological hormone that is secreted from beta-cells in the islets of Langerhans in the pancreas. Under normal physiological conditions, insulin is secreted in response to increased blood glucose levels and stimulates cellular glucose uptake stored as glycogen.

Type-1 diabetes is the failure to produce enough insulin and instead of being transported into cells, sugar builds up in the blood stream. In contrast, in Type-2 diabetes the body exhibits insulin resistance and fails to respond accordingly. Increased risk of developing Type-2 diabetes is more commonly associated with lifestyle factors, such as obesity.

Incretins are a group of metabolic hormones that stimulate a decrease in blood glucose levels. The study of how Incretins are released after eating and augment the secretion of insulin released from pancreatic beta cells of the islets of Langerhans by a blood glucose-dependent mechanism continues to advance. 

IBL-America offers investigators a broad range of quality laboratory kits to identify key biomarkers to achieve their research goals and study the biological processes underlying diabetes.

  • Insulin RIA

    Insulin RIA

    Immunoradiometric assay (IRMA) for the quantitative determination of human Insulin (INS) in serum. FDA registered 510(k) Exempt. For In-Vitro Diagnostic Use. Insulin, a polypeptide hormone with a molecular weight of 5800, is secreted by the beta...

    $261.00
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  • Vasoactive Intestinal Polypeptide (VIP)

    Vasoactive Intestinal Polypeptide (VIP)

    Radioimmunoassay (RIA) for the determination of Vasoactive Intestinal Polypeptide (VIP) in human plasma. For research use only, not for use in diagnostic procedures.<br><br> Vasoactive intestinal peptide (VIP) is a linear polypeptide...

    $906.00
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  • Glucagon ELISA

    Glucagon ELISA

    Glucagon is a 29-amino acid peptide that is produced from the cleavage of proglucagon (160 amino acids) by proprotein convertase 2 in pancreatic alpha cells. In intestinal Lā€cells, proglucagon is cleaved into glicentin, a 69 amino acid peptide. Glicentin...

    $570.00
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  • Insulin ELISA kit

    Insulin ELISA kit

    Enzyme immunoassay (ELISA) for the determination of Insulin in serum and plasma. FDA exempt, can be used for in-vitro diagnostics. Insulin is the principal hormone responsible for the control of glucose metabolism. It is synthesized in the...

    $284.00
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  • Soluble Leptin Receptor (sLEP-R) ELISA

    Soluble Leptin Receptor (sLEP-R) ELISA

    Enzyme immunoassay (ELISA) for the determination of soluble human leptin receptor (sLEP-R) in human serum or plasma. For research use only, not for use in diagnostic procedures.<br><br> The adipokine leptin realizes signal transduction via...

    $705.00
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  • Apolipoprotein A5 (ApoA5)

    Apolipoprotein A5 (ApoA5)

    Solid phase sandwich ELISA for the determination of Human ApoA5 in human serum and EDTA-plasma. For research use only, not for use in diagnostic procedures.<br><br> ApoA5 is a protein with 39kDa molecular weight that was discovered by...

    $827.00
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  • Intact Proinsulin

    Intact Proinsulin

    Sandwich enzyme-linked immunosorbent assay (ELISA) for the determination of intact proinsulin in mouse and rat EDTA-plasma, serum and cell culture supernatant. For research use only, not for use in diagnostic procedures.<br><br> Proinsulin...

    $827.00
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  • Mouse/Rat Total Insulin (high sensitivity) ELISA

    Mouse/Rat Total Insulin (high sensitivity) ELISA

    Sandwich enzyme-linked immunosorbent assay (ELISA) for the determination of total insulin in mouse and rat EDTA-plasma and serum. For research use only, not for use in diagnostic procedures. <br> <br> Insulin is peptide hormone that is...

    $827.00
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  • Leptin ELISA

    Leptin ELISA

    Ligand-Enzyme Immunoassay (ELISA) for the determination of functional, receptor binding Leptin in human serum and plasma (EDTA, Heparin). For research use only, not for use in diagnostic procedures.<br><br> Leptin a hormone of 146 amino...

    $1,946.00
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  • Insulin-like Growth Factor-Binding Protein-6 (IGFBP-6)

    Insulin-like Growth Factor-Binding Protein-6 (IGFBP-6)

    Enzyme-linked immunoassay (ELISA) for the determination of Insulin-like Growth Factor 6 (IGFBP-6) in serum, plasma, cell culture medium, and other body fluids. For research use only, not for use in diagnostic procedures.<br><br> The...

    $703.00
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  • Growth Hormone Binding Protein (GHBP)

    Growth Hormone Binding Protein (GHBP)

    Sandwich enzyme immunoassay (ELISA) for the determination of Growth Hormone Binding Protein (GHBP) in serum and plasma. For research use only, not for use in diagnostic procedures.<br><br> Growth Hormone Binding Protein (GHBP) consists of...

    $686.00
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