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Dock7 Anti-Human Rabbit IgG Affinity Purify 1

$132.00
SKU:
28057-S
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Small GTPase of Rho family is one of signaling factors which control alteration of cellular morphology, cell division and differentiation, and plays an important role in regulation of generation and organogenesis at an individual level. Its functions are strictly regulated and its dysfunction causes many diseases such as immunological disease or neurodegenerative disease. Dedicator of cytokinesis (Dock) 7 is a Rho family small GTPase activating factor (or exchange factor) activating Ras and Cdc42 specifically of the Rho family small GTPase, and is widely expressed molecule. It is noted that Dock7 is an important factor for proliferation and differentiation of neurocytes or glial cells since it is more expressed especially in both of the central and peripheral nerve tissues. Meanwhile, it is known that Dock7 makes a complex with products of responsible gene for tuberous sclerosis (Plingle disease), TSC1/2, therefore it is suggested that the relation with intellectual decline caused by brain tumor or vascular fibroma of the vessels where much TSC1/2 are expressed. There are proteins, called Dock6 and Dock8, very similar to Dock7 in human, however, their regulation systems are unknown yet. For research use only, not for use in diagnostic procedures.

application:
WB, IP, ICC
Catalog number:
28057-S
Datasheet:

Click for Datasheet

formulation:
Lyophilized product from 1% BSA in PBS containing 0.05% NaN3
immunogen:
Synthetic peptide of a part of Human Dock7 (KELFALHPSPDEEE)
MSDS:

Click for MSDS

notes:
For research use only, not for use in diagnostic procedures.
The datasheet for this product (see above) is intended to serve as an example only. Please refer to the datasheet provided with the antibody for precise details.
Other names:
Please see datasheet
Protocol:

Click for Antibody Protocol

purification:
Purified with antigen peptide
size:
5 µg
specificity:
Cross-reacts with rat
storage:
Lyophilized product, 5 years at 2 - 8 °C; Solution, 2 years at -20 °C.
Species:
Human
Host:
Rabbit