Two kinds of receptors for Endothelin have been found, namely Endothelin-A (ET-A) receptor and Endothelin-B (ET-B) receptor. ET-A receptor is ET-1 specific and expressed in lung, aorta, atrium, liver, muscle, cerebral cortex, cerebellum, kidney, adrenal, duodenum, colon and placenta at the mRNA or cDNA level, while ET-B receptor lacks isopeptide specificity and is found in liver, lung, placenta, kidney, heart and brain. Cellular localization of ET-receptors in these organs or tissues, however, has not been elucidated, although stromal cells, but not epithelial cells of the breast, express ET-1 receptor in vitro. For research use only, not for use in diagnostic procedures.
- application:
- IHC, WB
- Catalog number:
- 16201
- Datasheet:
- formulation:
- Lyophilized product from 1% BSA in PBS containing 0.05% NaN3
- immunogen:
- Synthetic peptide of C-terminal of Human ET-A receptor
- MSDS:
- notes:
- For research use only, not for use in diagnostic procedures.
The datasheet for this product (see above) is intended to serve as an example only. Please refer to the datasheet provided with the antibody for precise details. - Other names:
- Please see datasheet
- Protocol:
- purification:
- Affinity Purified with synthetic peptide
- size:
- 100 µg
- specificity:
- Cross-reacts with Bovine and Rat
- storage:
- Lyophilized product, 5 years at 2 - 8 °C; Solution, 2 years at -20 °C
- Species:
- Human
- Host:
- Rabbit
