ImmunoGuide® Enzyme immunoassay (ELISA) test kit for the determination of free antibodies directed against the drug Etanercept (Enbrel®) in serum and plasma.<br><br>
The drug Etanercept (trade name Enbrel®) is a dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. One of the major concerns, despite of its wide usage, is the potential development of anti-drug antibodies (ADA) which in turn may interfere with the drug efficacy as mainly judged by observing the relapse of signs and symptoms of disease and necessitate dose-escalation or potentially ending up the treatment.<br><br>
The ImmunoGuide Antibody to Etanercept ELISA Kit can be used for the measurement of free antibodies against this drug. It does not detect such antibodies which already are bound to the drug. For research use only, not for use in diagnostic procedures.
- Assay Description:
- 1 hour incubation (RT) + 1 hour (RT) + 15 min. (RT) = 2 hours, 15 min. total incubation time
- Catalog number:
- TM09007
- configuration:
- 96 Determinations, 12x8 removable strips
- controls:
- Positive control
- design:
- Enzyme immunoassay (ELISA) technique
- FDA Status:
- For research use only, not for use in diagnostic procedures
- MSDS:
- Available upon request
- notes:
- The protocol for this product (see above) is intended to serve as an example only. Please refer to the Instructions For Use provided with the assay kit for precise details.
- Protocol:
- Sample types:
- Serum and plasma
- Sample volume:
- 10 µL
- Standards:
- 5 Standards, ready to use
- Standard range:
- 0 / 3 - 1000 ng/mL
- storage:
- 2 - 8 °C
- sensitivity:
- 40 ng/mL
- Species:
- Human
- Products related:
- Etanercept (Enbrel®) ELISA
Etanercept (Enbrel®) (mAb-based) ELISA - Additional info:
