A new Girdin family molecule, Gipie is expressed in endothelial cells and it is induced by ER stresses. It interacts with GRP78 that is a 78kDa glucose regulatory protein. It has been reported that Gipie controls IRE1-JNK signal pathway by the interactive function and protects endothelial cells from apoptosis that is induced by ER stresses under circumstances such as atherosclerosis or vascular endothelial failure. For research use only, not for use in diagnostic procedures.
- application:
- IHC, ICC, WB, IP
- Catalog number:
- 28149
- Datasheet:
- formulation:
- Lyophilized product in PBS containing 1% BSA and 0.05% NaN3
- immunogen:
- Synthetic peptide of Gipie (VQEPEKRPLTPSLSQ)
- MSDS:
- notes:
- For research use only, not for use in diagnostic procedures.
The datasheet for this product (see above) is intended to serve as an example only. Please refer to the datasheet provided with the antibody for precise details. - Protocol:
- purification:
- Affinity purified with antigen peptide
- size:
- 100 µg
- specificity:
- Cross-react with Human Gipie
- storage:
- Lyophilized product, 5 years at 2 - 8 °C; Solution, 2 years at -20 °C.
- Species:
- Human
- Host:
- Rabbit
- Additional info:
