Neurofilaments are intermediate diameter (10nm) filaments that are located in neurons specifically. They are usually composed of three mid-diameter filament proteins, NfL, NfM, and NfH, and are associated with the maintenance of the inner diameter of nerves. Neurofilaments are expressed specifically in nerves and their expression increases after nerve injury from neurological or traumatic diseases. Therefore, they are attracting attention as biomarkers that reflect the state of neurological disorders. This ELISA kit specifically measures neurofilament light chain (NfL) in human CSF. For research use only, not for use in diagnostic procedures.
- Assay Description:
- Overnight incubation (2 - 8°C) + 60 min. (2 - 8°C) + 30 min. (RT) = Overnight + 1 hour 30 min total incubation time
- Catalog number:
- 27903
- configuration:
- 96 Determinations, 12x8 removable strips
- controls:
- None provided
- design:
- Enzyme immunoassay (ELISA) technique
- FDA Status:
- For research use only, not for use in diagnostic procedures
- notes:
- The protocol for this product (see above) is intended to serve as an example only. Please refer to the Instructions For Use provided with the assay kit for precise details.
- MSDS:
- Please Inquire
- Protocol:
- Sample types:
- Cerebrospinal fluids
- Sample volume:
- 100 μL of properly diluted unknown / determination
- standards:
- 7 standards, lyophilized
- Standard range:
- 0 / 48.4 - 3,100 pg/mL
- storage:
- 2 - 8 °C
- sensitivity:
- 10.2 pg/mL
- Species:
- Human
- References:
