Monoclonal Antibodies

Monoclonal antibodies (mAb or moAb) are derived from a single B-cell parent clone and therefore only recognize a single epitope per antigen.

These B-cells are immortalized by fusion with hybridoma cells, allowing for long-term generation of identical monoclonal antibodies.

Monoclonal antibodies specifically detect a particular epitope on the antigen and therefore are less likely than polyclonal antibodies to cross-react with other proteins.

IBL-America offers a wide range of monoclonal antibodies that can be used in the research and development of multiple laboratory testing applications.

CRMP-2 (N3E) Anti-Human Mouse IgG MoAb 1

CRMP-2 (Collapsin response mediator protein-2) is highly expressed in the developing nervous system and identified as protein involved in Semaphorin 3A (Collapsin-1) intracellular signaling. It is reported that the mutation of unc-33, a Caenorhabditis...

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CRMP-2 (C4G) Anti-Human Mouse IgG MoAb 1

CRMP-2 (Collapsin response mediator protein-2) is highly expressed in the developing nervous system and identified as protein involved in Semaphorin 3A (Collapsin-1) intracellular signaling. It is reported that the mutation of unc-33, a Caenorhabditis...

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COX-2 (13H14) Anti-Human Mouse IgG MoAb 1

Cyclooxygenase (COX) is a membrane bound enzyme responsible for the oxidation of arachidonic acid to Prostaglandin G2 (PGG2) and the subsequent reduction of PGG2 to PHG2.

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ApoE4 (5B5) Anti-Human Mouse IgG MoAb 1

Apolipoprotein E (ApoE) is a structural component of very low-density lipoprotein (VLDL) synthesized by the liver and intestinally synthesized chylomicrons. It is also a constituent of a subclass of high-density lipoproteins (HDLs) involved in...

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Amyloid Beta ( 11-28 ) ( 12B2 ) Aβ Anti-Human Mouse IgG MoAb 1

Alzheimer's disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid (Aβ) peptide, a 40 to 43 amino acid...

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τ/Amino Junction (9A1) Anti-Human Mouse IgG MoAb 1

Tau protein is a microtubule-associated protein expressed in neuroaxon and has molecular weight of 50~70 kDa. Some Alzheimer's patients have sites where tau protein is accumulated abnormally. It is known that six isoforms of tau protein formed by...

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14-3-3τ Protein (33A) Anti-Human Mouse IgG MoAb 1

The 14-3-3 proteins are a family of conserved regulatory molecules expressed in all eukaryotic cells. A striking feature of the 14-3-3 proteins is their ability to bind a multitude of functionally diverse signaling proteins, including kinases,...

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14-3-3 γ Protein (63A1) Anti-Human Mouse IgG MoAb 1

The 14-3-3 proteins are a family of conserved regulatory molecules expressed in all eukaryotic cells. A striking feature of the 14-3-3 proteins is their ability to bind a multitude of functionally diverse signaling proteins, including kinases,...

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C-ERC/Mesothelin (22A31) Anti-Human Mouse IgG MoAb

Erc has been identified as a gene showing stronger expression in cancer-affected renal cell than in normal renal tissue in Eker rats (a rat model of renal cancer). The human homologue of the protein encoded by this gene is called MPF (megakaryocyte...

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Tau (Phosphorylated) (C5) Anti-Human Mouse IgG MoAb

Tau protein is a microtubule-associated protein expressed in neuroaxon and has molecular weight of 50 - 70 kDa. Some Alzheimer's patients have sites where tau protein is accumulated abnormally. This antibody reacts with phosphorylated part in amino acid...

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Anti-TP (ATYMPMAB) Mouse IgG MoAb

Thymidylate synthase/TS (EC 2.1.1.45), Dihydropyrimidine dehydrogenase/DPD (EC 1.3.1.2), Thymidine phosphorylase/TP (EC 2.4.2.4) and Orotate phosphoribosyl transferase/OPRT (EC 2.4.2.10) are known as key enzymes related to nucleic-acid metabolism within...

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NP95 (mt40) Anti-Human Mouse IgG MoAb

Np95 has been originally found as a tumor-specific nuclear antigen of 95kDa in mice. Experiments using B10 strains showed that Np95 is enriched in precancerous cells and is abnormally expressed throughout cell cycle in radiation-induced lymphomatoid...

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