Monoclonal Antibodies

Monoclonal antibodies (mAb or moAb) are derived from a single B-cell parent clone and therefore only recognize a single epitope per antigen.

These B-cells are immortalized by fusion with hybridoma cells, allowing for long-term generation of identical monoclonal antibodies.

Monoclonal antibodies specifically detect a particular epitope on the antigen and therefore are less likely than polyclonal antibodies to cross-react with other proteins.

IBL-America offers a wide range of monoclonal antibodies that can be used in the research and development of multiple laboratory testing applications.

MBD3 (Methyl-CpG-Binding Protein 3) (3A3) Anti-Human Mouse IgG MoAb

Methylation at CpG dinucleotides in genomic DNA is a fundamental epigenetic mechanism of gene expression control in vertebrates. Proteins with a methyl-CpG binding domain (MBD) can bind to single methylated CpGs and most of them are involved in...

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Lag (Langerhans Cells), (4D12) Anti-Human Mouse IgG MoAb

Langerhans cells (LC) were reported to function as the antigen-presenting cells in the skin. They express immune response gene-associated antigens on their cell membranes. These cells seem to mediate contact sensitivity in vivo and the antigen-specific...

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KGF (8A4) Anti-Human Mouse IgG MoAb

Keratinocyte Growth Factor (KGF) is a growth factor which affects epithelial cells specifically and it hardly affects mesenchymal cells like fibroblasts. Its receptor is K-sam, and it is said that the signals of differentiation and proliferation will be...

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KGF (5J2) Anti-Human Mouse IgG MoAb

Keratinocyte Growth Factor (KGF) is a growth factor which affects epithelial cells specifically and it hardly affects mesenchymal cells like fibroblasts. Its receptor is K-sam, and it is said that the signals of differentiation and proliferation will be...

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KGF (11F1) Anti-Human Mouse IgG MoAb

Keratinocyte Growth Factor (KGF) is a growth factor which affects epithelial cells specifically and it hardly affects mesenchymal cells like fibroblasts. Its receptor is K-sam, and it is said that the signals of differentiation and proliferation will be...

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Intelectin-1 (3G9) Anti-Human Mouse IgG MoAb

Intelectin-1 is a secretory animal lectin that binds to galactofuranose. Human intelectin-1 is a glycoprotein mainly secreted from intestinal goblet cells. It was reported that the protein was related to inflammation or parasite infection. Recently, it...

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IDH1 R132S (SMab-1) Anti-Human Mouse IgG MoAb

Specific mutations in the isocitrate dehydrogenase 1 gene IDH1 have been found in several brain tumors including astrocytoma, oligodendroglioma and glioblastoma multiforme, with mutations found in nearly all cases of secondary glioblastomas, but rarely...

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IDH1 R132H (HMab-1) Anti-Human Mouse IgG MoAb

Specific mutations in the isocitrate dehydrogenase 1 gene IDH1 have been found in several brain tumors including astrocytoma, oligodendroglioma and glioblastoma multiforme, with mutations found in nearly all cases of secondary glioblastomas, but rarely...

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Hepatic Sinusoidal Endothelial Cells (SE-1) Anti-Rat Mouse IgG MoAb

Among the vascular endothelial cells, hepatic sinusoidal endothelial (HSE) cells are morphologically unique because they have open fenestrations in their cytoplasm and lack basal lamina.

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GRO/CINC-1 (6G2) (C) Anti-Rat Mouse IgM MoAb

Cytokine-induced neutrophil chemo attractant 1(CINC-1) was originally purified from media conditioned by IL-1 β stimulated rat kidney epithelioid cells (NRK-52E).

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GRO/CINC-1 (2A9) (N) Anti-Rat Mouse IgG MoAb

Cytokine-induced neutrophil chemo attractant 1(CINC-1) was originally purified from media conditioned by IL-1 β stimulated rat kidney epithelioid cells (NRK-52E).

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GFAP (G-25-8-3) Anti-Bovine Mouse IgG MoAb

GFAP (Glial fibrillary acidic protein) is acidic protein which has molecular weight of 50 kDa, and the protein is the principal constituent of glial fibra acidic protein. As GFAP exists in astroglia specifically, this antibody can be used as a marker...

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