Monoclonal Antibodies

Monoclonal antibodies (mAb or moAb) are derived from a single B-cell parent clone and therefore only recognize a single epitope per antigen.

These B-cells are immortalized by fusion with hybridoma cells, allowing for long-term generation of identical monoclonal antibodies.

Monoclonal antibodies specifically detect a particular epitope on the antigen and therefore are less likely than polyclonal antibodies to cross-react with other proteins.

IBL-America offers a wide range of monoclonal antibodies that can be used in the research and development of multiple laboratory testing applications.

IDH1 R132H

Isocitrate Dehydrogenase 1 (IDH1) is a soluble, cytosolic enzyme involved in the TCA metabolic cycle. The most notable mutation in this enzyme, R132H, is clinically indicated in the majority of astrocytomas and oligodendroglial tumours, with the mutation...

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Total Vitamin D derivative - Carboxylic acid (COOH)

Over the years IBL-America has built partnerships with suppliers with extensive experience in Vitamin D immunoassay development and Vitamin D chemistry. We can provide all components to develop your own Vitamin D assay. Based on a proprietary Vitamin D...

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Anti-SSEA-3 (15B11) Mouse IgG MoAb 1

SSEA-3 (stage specific embryonic antigen 3), one of the sphingoglycolipid species, is expressed on the surface of the Muse (Multilineage-differentiating Stress Enduring) cells as well as human EC (Embryonic carcinoma) cells, ES (Embryonic stem) cells and...

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25OH Vitamin D2/D3 MoAb, Clone LMBP 7011CB

For Monoclonal Antibodies, a careful selection process of ensures a superior specificity profile. Moreover, state of the art production techniques ensure a constant and renewable source of antibodies and all batches are identical. These monoclonal...

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25OH Vitamin D2/D3 MoAb, Clone LMBP 7012CB

For Monoclonal Antibodies, a careful selection process ensures a superior specificity profile. Moreover, state of the art production techniques ensure a constant and renewable source of antibodies and all batches are identical. These monoclonal...

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C-ERC/Mesothelin (22A31) Anti-Human Mouse IgG MoAb 1

Erc has been identified as a gene showing stronger expression in cancer-affected renal cell than in normal renal tissue in Eker rats (a rat model of renal cancer). The human homologue of the protein encoded by this gene is called MPF (megakaryocyte...

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CRMP-2 (Phosphorylated) (3F4) Anti-Human Mouse IgG MoAb 1

CRMP-2 (Collapsin response mediator protein-2) is highly expressed in the developing nervous system and identified as protein involved in Semaphorin 3A (Collapsin-1) intracellular signaling. It is reported that the mutation of unc-33, a Caenorhabditis...

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p16 INK4a (1H4) Anti-Human Mouse IgG MoAb 1

p16INK4a is a cyclin-dependent kinase (CDK) inhibitor, and binds CDK4 and CDK6 and inhibits their kinase activity. It is also called MTS1 and INK4a, and p15INK4b (MTS2), p18INK4c and p19INK4d are other members of the INK4 family. p16INK4a is a tumor...

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Tau (Phosphorylated) (C5) Anti-Human Mouse IgG MoAb 1

Tau protein is a microtubule-associated protein expressed in neuroaxon and has molecular weight of 50 - 70 kDa. Some Alzheimer's patients have sites where tau protein is accumulated abnormally. This antibody reacts with phosphorylated part in amino acid...

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Anti-TP (ATYMPMAB) Mouse IgG MoAb 1

Thymidylate synthase/TS (EC 2.1.1.45), Dihydropyrimidine dehydrogenase/DPD (EC 1.3.1.2), Thymidine phosphorylase/TP (EC 2.4.2.4) and Orotate phosphoribosyl transferase/OPRT (EC 2.4.2.10) are known as key enzymes related to nucleic-acid metabolism within...

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NP95 (mt40) Anti-Human Mouse IgG MoAb 1

Np95 has been originally found as a tumor-specific nuclear antigen of 95kDa in mice. Experiments using B10 strains showed that Np95 is enriched in precancerous cells and is abnormally expressed throughout cell cycle in radiation-induced lymphomatoid...

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Reticulocalbin-1 (TMU-6A1) Anti-Human Mouse IgG MoAb 1

Human Reticulocalbin-1 is a 44kDa protein and belongs to the EF (elongation factor) -hand calcium-binding protein family, and it is known as a luminal protein of endoplasmic reticulum (ER) with the C-terminal HDEL (ER retention signal) sequence. Although...

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