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Anti-Smad3L (S213 Phosphorylated) (5A11) Mouse IgG MoAb 1
Phosphorylation of signal transduction molecules Smad3, can be an important information for understanding of various biological functions of transforming growth factor (TGF)-β. TGF-β type I receptor and mitogen activated protein kinase (MAPK)...
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YB-1 (21A3) Anti-Human Mouse IgG MoAb 1
YB-1 (Y-box binding protein-1) contains a highly conserved cold shock domain and is a transcription factor that binds to a CCAAT box. It has been reported that P-glycoprotein is highly expressed in cisplatin-resistant cancer cell lines since the sequence...
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VEGF (2E1) Anti-Human Mouse IgG MoAb 1
Vascular Endothelial Cell Growth Factor (VEGF) is a homodimeric protein initially purified from media conditioned by normal bovine pituitary folliculo-stellate cells and secreted by a variety of vascularized tissues. It was subsequently found to be...
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Anti-Tob (4B1) Mouse IgG MoAb 1
Tob (Transducing molecule of c-ErbB-2) was identified as a molecule that binds to the receptor tyrosine kinase c-ErbB2 in 1996. After that, Tob2, BTG1, PC3/TIS21/BTG2, ANA, PC3B etc were found as proteins with a homologous region at about 110...
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Tenascin-C (EGF Like Domain) (4F10TT) Anti-Human Mouse IgG 1
Tenascin-C (TN-C) is a component of the extracellular matrix (ECM) that has been shown to be involved in tissue interactions during fetal development and oncogenesis. It is glycoprotein consisting of six disulphide monomer isoforms being generated by...
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Tenascin-C (Domain B) (4C8MS) Anti-Human Mouse IgG MoAb 1
Tenascin-C (TN-C) is a component of the extracellular matrix (ECM) that has been shown to be involved in tissue interactions during fetal development and oncogenesis. It is glycoprotein consisting of six disulphide monomer isoforms being generated by...
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TEK/Tie-2 (2A1) Anti-Human Mouse IgG MoAb 1
TEK, also known as Tie-2 (Tyrosine kinase with Ig-like loops and Epidermal growth factor homology domains-2) and CD202b, is a 145 kDa receptor tyrosine kinase expressed on endothelial cells and hematopoietic cells. Its structure possesses an...
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SP-A (PE10) Anti-Human Mouse IgG MoAb 1
Lung surfactant is a lipoprotein complex which is synthesized and secreted into the alveoli of the lung by type II pneumocytes. Its major protein component, surfactant protein-A (SP-A), is a glycoprotein with a reduced denatured molecular mass of 35 kDa,...
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RGMa (410-10) Anti-Human Mouse IgG MoAb 1
RGMa (Repulsive Guidance Molecule a) is a GIP-anchored protein, about 33 kDa, and it is implicated in axonal guidance and neural tube closure of embryonic retina. It has reported as a potent inhibitor of axonal regeneration in the adult central nervous...
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Anti-Platelets (KOR-P77) Mouse IgG MoAb 1
Among myelocytic leukemia, megakaryocytic leukemia is caused by the canceration of megakaryocytes or megakaryoblasts which produce platelets. Some platelet antigens are used for the search of megakaryotic cells. It has been reported that this monoclonal...
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Parkin (5A1) Anti-Human Mouse IgG MoAb 1
Parkinson's Disease (PD) is a relatively common neurodegenerative disorder, which is characterized by the loss of midbrain dopamine (DA) neurons and the presence of Lewy bodies, proteinaceous cytoplasmic inclusions that are abundantly enriched in...
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Parkin (1A1) Anti-Human Mouse IgG MoAb 1
Parkinson's Disease (PD) is a relatively common neurodegenerative disorder, which is characterized by the loss of midbrain dopamine (DA) neurons and the presence of Lewy bodies, proteinaceous cytoplasmic inclusions that are abundantly enriched in...
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Monoclonal Antibodies
Monoclonal antibodies (mAb or moAb) are derived from a single B-cell parent clone and therefore only recognize a single epitope per antigen.
These B-cells are immortalized by fusion with hybridoma cells, allowing for long-term generation of identical monoclonal antibodies.
Monoclonal antibodies specifically detect a particular epitope on the antigen and therefore are less likely than polyclonal antibodies to cross-react with other proteins.
IBL-America offers a wide range of monoclonal antibodies that can be used in the research and development of multiple laboratory testing applications.