Polyclonal Antibodies

Polyclonal antibodies (pAbs) are a combination of antibodies, derived from the immune response of multiple B-cells, and each one recognizes a different epitope on the same antigen.

Polyclonals are produced by injecting an animal with an antigen. This elicits the immune response that produces antibodies against that antigen. The polyclonal immunoglobulins are then purified from the animal’s blood serum.

IBL-America offers a wide range of polyclonal antibodies that can be used in research using multiple laboratory testing methods.

14-3-3 η Protein Anti-Human Rabbit IgG Affinity Purify

The 14-3-3 proteins are a family of conserved regulatory molecules expressed in all eukaryotic cells. A striking feature of the 14-3-3 proteins is their ability to bind a multitude of functionally diverse signaling proteins, including kinases,...

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Anti-Human Girdin (Phospho-Y1764) Rabbit IgG (Affinity Purify)

Girdin is a new protein playing an important role in the infiltration and metastasis of cancer cells. A new substance of Akt, Girdin (Girders of actin filament) was discovered by a research group led by Takahashi et al., Nagoya University by screening...

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LRAT (Lecithin Retinol Acyltransferase) (031) Anti-Human Rabbit IgG A.P. (Affinity Purify)

LRAT is a retinol-esterifying enzyme and it is mainly found in G0 stage of stellate cells (Ito cells) in liver. At stellate cells, LRAT is thought to take a role engulfing and pooling excess vitamin A released from hepatocytes. As normal hepatocytes are...

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Gipie Anti-Human Rabbit IgG Affinity Purify

A new Girdin family molecule, Gipie is expressed in endothelial cells and it is induced by ER stresses. It interacts with GRP78 that is a 78kDa glucose regulatory protein. It has been reported that Gipie controls IRE1-JNK signal pathway by the...

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Daple Anti-Human Rabbit IgG Affinity Purify

Classical (β-catenin dependent) and non-classical (β-catenin non-dependent) Wnt signal pathway are signal pathways that regulate forming and maintaining of embryonic growth or cell structures of organs and amplifying of cells. It is also...

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CAD (2194) Anti-Human Rabbit IgG Affinity Purify

mTOR is a target molecule in mammalian used in rapamycin drug and it has been recognized as a central molecule that has a role of signaling for regulating proliferation and cell growth. Since DNA replication is essential for proliferation, regulating...

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Gastrin Receptor (OK-524) Anti-Human Rabbit IgG Affinity Purify

Gastrin is one of the most important gut-related hormones contributing to gastric acid secretion. Gastrin and the gastrin receptor (GR) are co-expressed in many gastrointestinal cancer cell lines, and gastrin is regarded as an autocrine growth factor for...

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Podoplanin Anti-Human Rabbit IgG Affinity Purify

Podoplanin belongs to a type-I transmembrane protein which is a sialoglyco protein with some O-glycosylation sites. It is known as a lymphatic endothelium-specific marker and believed to have a platelet-aggregating activity and to promote hematogenous...

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RGMa Anti-Rat Rabbit IgG Affinity Purify

RGMa (Repulsive Guidance Molecule a) is a GIP-anchored protein, about 33 kDa, and it is implicated in axonal guidance and neural tube closure of embryonic retina. It has reported as a potent inhibitor of axonal regeneration in the adult central nervous...

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Anti-SEP1 Rabbit IgG Affinity Purify

SEP1 has been reported by group of Takahashi, as a gene enhancing its expression by stimulation by a neurotrophic factor, GDNF. Though SEP1 is found in every organ, it is located at neurite of neuroblastoma cells of which differentiation is induced by...

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Anti-GZF1 Rabbit IgG Affinity Purify

GZF1 has been identified as a gene whose expression is induced by a neurotrophic factor, GDNF. It codes a protein which has BTB/POZ domain in its N-terminal region and 10 of zinc finger motifs in its C-terminal area from the center. It has been known by...

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Anti-α2, 6-Sialyltransferase (C) Rabbit IgG Affinity Purify

The histopathological picture of Alzheimer’s disease is characterized by senile plaques and neurofibrillary tangles, and because the senile plaques form first, they are considered the initial lesion. Senile plaques are known to be formed by...

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