Polyclonal Antibodies

Polyclonal antibodies (pAbs) are a combination of antibodies, derived from the immune response of multiple B-cells, and each one recognizes a different epitope on the same antigen.

Polyclonals are produced by injecting an animal with an antigen. This elicits the immune response that produces antibodies against that antigen. The polyclonal immunoglobulins are then purified from the animal’s blood serum.

IBL-America offers a wide range of polyclonal antibodies that can be used in research using multiple laboratory testing methods.

RGMa Anti-Rat Rabbit IgG Affinity Purify 1

RGMa (Repulsive Guidance Molecule a) is a GIP-anchored protein, about 33 kDa, and it is implicated in axonal guidance and neural tube closure of embryonic retina. It has reported as a potent inhibitor of axonal regeneration in the adult central nervous...

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Anti-SEP1 Rabbit IgG Affinity Purify 1

SEP1 has been reported by group of Takahashi, as a gene enhancing its expression by stimulation by a neurotrophic factor, GDNF. Though SEP1 is found in every organ, it is located at neurite of neuroblastoma cells of which differentiation is induced by...

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Anti-GZF1 Rabbit IgG Affinity Purify 1

GZF1 has been identified as a gene whose expression is induced by a neurotrophic factor, GDNF. It codes a protein which has BTB/POZ domain in its N-terminal region and 10 of zinc finger motifs in its C-terminal area from the center. It has been known by...

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Anti-APP (Phosphorylated) Rabbit IgG Affinity Purify 1

Amyloid precursor protein (APP) is precursor protein of Amyloid β which is major constituent of senile plaque in Alzheimer's disease. It is known that there are three major isoforms, APP695, APP751 and APP770, and are generated from alternative...

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Anti-α2, 6-Sialyltransferase (C) Rabbit IgG Affinity Purify 1

The histopathological picture of Alzheimer’s disease is characterized by senile plaques and neurofibrillary tangles, and because the senile plaques form first, they are considered the initial lesion. Senile plaques are known to be formed by...

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dbpA Anti-Human Rabbit IgG Affinity Purify 1

DbpA (DNA Binding protein A) belongs to the Y-box binding protein family that contain a DNA binding domain, called the cold shock domain, of about 80-amino-acid residues. DbpA was identified as the protein binding to the epidermal growth factor receptor...

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Claudin-8 (C) Anti-Mouse Rabbit IgG Affinity Purify 1

Claudin is a transmembrane protein that 4 times goes through the membrane to be formed a gene family and a tight junction molecule that is involved in cell to cell adhesion of epithelial and endothelial cell sheets. It also gets together among several...

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RIG-I (CTD) Anti-Human Rabbit IgG Affinity Purify 1

RIG-I (retinoic acid inducible gene-I) is one of cytoplasmic viral sencers which has a RNA helicase domain and it is believed to recognize virus-derived double-stranded RNA (dsRNA). It is considered that RIG-I normally exist as inactive form in cytoplasm...

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CyCAP (74) Anti-Rat Rabbit IgG Affinity Purify 1

CyCAP is a binding protein for cyclophilin C in competition with cyclosporine. It is present in brain, kidney and macrophage cells and is known as an inflammation-related protein. In recent years, it has been reported that CyCAP forms complexes with...

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CD109 (641) Anti-Human Rabbit IgG Affinity Purify 1

CD109 is a glycosyl-phosphatidyl-inositol (GPI) - anchored glycoprotein about 180 - 190 kDa. It is shown that CD109 is expressed in vascular endothelial cells, some epithelial cells, activated T-cells and platelets, and subset of CD34+ megakaryocytic...

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Tti1/KIAA0406 Anti-Human Rabbit IgG Affinity Purify 1

Mammalian target of rapamycin (mTOR), a member of the phosphatidylinositol 3-kinase-related kinase (PIKK), is a major regulator of translation, cell growth, and autophagy. mTOR constitutes two distinct complexes, mTORC1 and mTORC2, that differ in their...

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c-MPL-P(M617) Anti-Human Rabbit IgG Affinity Purify 1

The c-mpl proto oncogene was first identified as the cellular homolog of the viral oncogene v-mpl in the myeloproliferative leukemia virus (MPLV). However, based on homology with a member of the cytokine receptor superfamily, the c-mpl gene was predicted...

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