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RAAS Pathway

The Renin-Angiotensin-Aldosterone System (RAAS) also known as the Renin-Angiotensin System (RAS) is a multi-hormonal system that coordinates a variety of physiological processes for proper regulation of blood volume and pressure.

RAAS regulates sodium and water absorption in the kidney, thus directly having an impact on systemic blood pressure.

Typically, RAAS is activated when there is a drop in blood pressure (reduced blood volume) to increase water and electrolyte reabsorption in the kidney; which compensates for the drop in blood volume, thus increasing blood pressure.

When renin is released into the blood, it acts upon a circulating substrate, angiotensinogen, that undergoes proteolytic cleavage to form the decapeptide angiotensin I. Vascular endothelium, particularly in the lungs, has an enzyme, angiotensin converting enzyme (ACE), that cleaves off two amino acids to form the octapeptide, angiotensin II (AII), although many other tissues in the body (heart, brain, vascular) also can form AII.

  • ACE2

    ACE2

    The Human Angiotensin-converting enzyme 2 (ACE2) ELISA has been designed for the  detection of human ACE2 in serum, plasma, tissue homogenates or other biological fluids. For research use only, not for use in diagnostic...

    $683.00
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  • Aldosterone ELISA

    Aldosterone ELISA

    Competitive enzyme-linked immunosorbent assay (ELISA) for the determination of Aldosterone in serum, plasma or urine. For research use only, not for use in diagnostic procedures.

    $386.00
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  • Aldosterone RIA

    Aldosterone RIA

    Radioimmunoassay for the determination of Aldosterone in human serum and urine. For research use only, not for use in diagnostic procedures.

    $432.00
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  • Angiotensin II

    Angiotensin II

    Radioimmunoassay (RIA) for the determination of angiotensin II in EDTA plasma. For research use only, not for use in diagnostic procedures.

    $873.00
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  • Angiotensinogen (104AT 601.2.80) Anti-Human Mouse IgG MoAb

    Angiotensinogen (104AT 601.2.80) Anti-Human Mouse IgG MoAb

    Angiotensinogen is the precursor of angiotensin and is cleaved into angiotensin I and II in the renin-angiotensin system, and it has long been reported to play an important role in controlling blood pressure. In recent years interest related to the role...

    $550.00
    Add to Cart
  • Angiotensinogen (104AT 601.2.80) Anti-Human Mouse IgG MoAb  1

    Angiotensinogen (104AT 601.2.80) Anti-Human Mouse IgG MoAb 1

    Angiotensinogen is the precursor of angiotensin and is cleaved into angiotensin I and II in the renin-angiotensin system, and it has long been reported to play an important role in controlling blood pressure. In recent years interest related to the role...

    $132.00
    Add to Cart
  • Angiotensinogen (405) Anti-Mouse/Rat Rabbit IgG Affinity Purify

    Angiotensinogen (405) Anti-Mouse/Rat Rabbit IgG Affinity Purify

    Angiotensinogen is the precursor of angiotensin and is cleaved into angiotensin I and II in the renin-angiotensin system, and it has long been reported to play an important role in controlling blood pressure. In recent years interest related to the role...

    $550.00
    Add to Cart
  • Angiotensinogen (405) Anti-Mouse/Rat Rabbit IgG Affinity Purify 1

    Angiotensinogen (405) Anti-Mouse/Rat Rabbit IgG Affinity Purify 1

    Angiotensinogen is the precursor of angiotensin and is cleaved into angiotensin I and II in the renin-angiotensin system, and it has long been reported to play an important role in controlling blood pressure. In recent years interest related to the role...

    $132.00
    Add to Cart
  • Angiotensinogen (Total)

    Angiotensinogen (Total)

    Angiotensinogen. Solid phase sandwich ELISA for the determination of human Total Angiotensinogen in serum, EDTA-plasma, urine, or cell culture media. For research use only, not for use in diagnostic procedures.<br><br> Angiotensinogen is the...

    $827.00
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  • Human Angiotensinogen (Intact)

    Human Angiotensinogen (Intact)

    Solid phase sandwich ELISA for the determination of human Intact Angiotensinogen ELISA in serum, EDTA-plasma, and urine. For research use only, not for use in diagnostic procedures.<br><br> Angiotensinogen is the precursor of angiotensin and...

    $827.00
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  • Mouse Angiotensinogen (Total)

    Mouse Angiotensinogen (Total)

    Solid phase sandwich ELISA for the determination of mouse Total Angiotensinogen ELISA in serum, EDTA-plasma and cell culture supernatant. For research use only, not for use in diagnostic procedures. <br><br> Angiotensinogen is a precursor...

    $827.00
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  • Mouse Intact Angiotensinogen

    Mouse Intact Angiotensinogen

    Solid phase sandwich ELISA for the determination of Intact Angiotensinogen (Full Length Angiotensinogen) in mouse serum and plasma samples. For research use only, not for use in diagnostic procedures. <br><br> Angiotensinogen is a...

    $827.00
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