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Plasma Renin Activity (PRA) ELISA Kit
Enzyme immunoassay (ELISA) for the determination of Plasma Renin Activity (PRA) in human EDTA plasma. For research use only, not for use in diagnostic procedures.<br><br> Measurement of PRA is important for the research of hypertensive...
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Rat Angiotensinogen (Total)
Solid phase sandwich ELISA for the determination of rat Total Angiotensinogen ELISA in serum, EDTA-plasma, urine and cell culture supernatant. For research use only, not for use in diagnostic procedures. <br><br> Angiotensinogen is a...
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Rat Intact Angiotensinogen
Solid phase sandwich ELISA for the determination of Intact Angiotensinogen (Full Length Angiotensinogen) in rat serum and plasma samples. For research use only, not for use in diagnostic procedures. <br><br> Angiotensinogen is a...
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Renin
Immunoradiometric assay (IRMA) for the determination of active Renin in human EDTA plasma. For research use only, not for use in diagnostic procedures.
Choose Options$699.00 -
Soluble (Pro)renin Receptor
(Pro)renin receptor/(P)RR is a common receptor protein between renin and prorenin. It has an ability at an equivalent level as renin to bind angiotensinogen and a catalytic activity for conversion from angiotensinogen to angiotensin I once it binds to...
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Urine Reagent Set for Aldosterone ELISA
Urine Reagent Set to be used exclusively with the Aldosterone ELISA (IB79134). Before use, read carefully the Instructions for Use provided with the Aldosterone ELISA (IB79134) kit.
Add to Cart$104.00
RAAS Pathway
The Renin-Angiotensin-Aldosterone System (RAAS) also known as the Renin-Angiotensin System (RAS) is a multi-hormonal system that coordinates a variety of physiological processes for proper regulation of blood volume and pressure.
RAAS regulates sodium and water absorption in the kidney, thus directly having an impact on systemic blood pressure.
Typically, RAAS is activated when there is a drop in blood pressure (reduced blood volume) to increase water and electrolyte reabsorption in the kidney; which compensates for the drop in blood volume, thus increasing blood pressure.
When renin is released into the blood, it acts upon a circulating substrate, angiotensinogen, that undergoes proteolytic cleavage to form the decapeptide angiotensin I. Vascular endothelium, particularly in the lungs, has an enzyme, angiotensin converting enzyme (ACE), that cleaves off two amino acids to form the octapeptide, angiotensin II (AII), although many other tissues in the body (heart, brain, vascular) also can form AII.