Raptor (regulatory associated protein of mTOR) is an about 150 kDa protein which has HEAT repeats and WD40 repeats, and it is identified as an mTOR binding protein. It is conserved over species and widely expressed in a variety of cells, and is also one of configuration factors of mTORC1/mTOR complex 1, which controls proteosynthesis and/or growth of cells along with mLST8. Raptor binds to p70 S6 kinase or 4E-BP1 (eukaryotic translation initiation factor 4E binding protein 1) which is a substrate of mTOR, through the mediation of TOS (TOR signaling) motif, and it plays an important role as a scaffold protein in phosphorylation of the substrate by mTOR.
- application:
- WB, IP
- Catalog number:
- 28011-S
- Datasheet:
- formulation:
- Lyophilized product from 1% BSA in PBS containing 0.05% NaN3
- immunogen:
- Synthetic peptide of the middle part of Human Raptor (IRKEREWRFLRNSRVRRQA)
- MSDS:
- notes:
- For research use only, not for use in diagnostic procedures.
The datasheet for this product (see above) is intended to serve as an example only. Please refer to the datasheet provided with the antibody for precise details. - Other names:
- Please see datasheet
- Protocol:
- purification:
- Purified with antigen peptide
- size:
- 10 µg
- specificity:
- Please see datasheet
- storage:
- Lyophilized product, 5 years at 2 - 8 °C; Solution, 2 years at -20 °C.
- Species:
- Human
- Host:
- Rabbit
- References:
