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sAPPβ-sw (6A1) Anti-Human Mouse IgG MoAb 1

$132.00
SKU:
10321-S
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Amyloidβ is derived by the sequential cleavage of amyloid precursor protein (APP) by betaand gamma-secretases. A double missense mutation (Lys670→Asn and Met671→Leu) in APP found in a Swedish pedigree (APPβ-sw) elevates Abeta40 and Abeta42 production (1), and the mutation is utilized in establishment of transgenic mice overexpress a mutant form of human amyloid precursor protein (2). Amyloidβproduction and, beta-secretase cleavage of APP β -sw reportedly occur in the endoplasmic reticulum (ER), Golgi and endocytic compartments (3).

application:
WB, Immunoprecipitation.
Catalog number:
10321-S
clone:
6A1
concentration:
Please see datasheet.
Datasheet:

Click for Datasheet

formulation:
Lyophilized product from 1% BSA in PBS containing 0.05%NaN3
immunogen:
Synthetic peptide for C-Terminal of Human sAPPβ-sw (ISEVNL)
isotype:
IgG3
MSDS:

Click for MSDS

notes:
For research use only, not for use in diagnostic procedures.
The datasheet for this product (see above) is intended to serve as an example only. Please refer to the datasheet provided with the antibody for precise details.
Other names:
Soluble βAmyloid Precursor Protein -Swedish
Protocol:

Click for Antibody Protocol

size:
10 µg
storage:
Lyophilized product, 5 years at 2 €“ 8 „ƒ, Solution, 2 years at €“20 „ƒ
Species:
Human
Host:
Mouse
Additional info:

Click for Pamphlet