Enzyme immunoassay (ELISA) for the direct quantitative determination of Total Estrogens in human serum. 510(k) exempt - for in vitro diagnostic use only.<br><br>
Total estrogens comprise the total quantity of estrone, estradiol, and estriol. The estrogens are involved in the development of female sex organs and secondary sex characteristics. Before the ovum is fertilized the main action of the estrogens is on the growth and function of the reproductive tract to prepare it for the fertilized ovum.<br><br>
During the follicular phase of the menstrual cycle the total estrogens level shows a slight increase. The production of total estrogens then increases markedly to peak at around day 13. The peak is of short duration and by day 16 of the cycle levels will be low. A second peak occurs at around day 21 of the cycle; if fertilization does not occur, the production of total estrogens decreases.<br><br>
In post-menopausal women the concentration of all estrogens decreases substantially and estrone becomes the predominant estrogen. In pregnant women the concentration of all estrogens escalates and estriol becomes the predominant estrogen.
- Assay Description:
- 30 minute incubation (RT) + 120 minute incubation (RT) + 30 minute incubation (RT)
- Catalog number:
- IB59134
- configuration:
- 96 Determinations, 8x12 removable strips
- controls:
- 2 controls, ready to use
- design:
- Enzyme immunoassay (ELISA) technique
- FDA Status:
- 510(k) exempt - IVD
- notes:
- The protocol for this product (see above) is intended to serve as an example only. Please refer to the Instructions For Use provided with the assay kit for precise details.
- Protocol:
- Sample types:
- Serum
- Sample volume:
- 50 µL
- standards:
- 7 standards, ready to use
- Standard range:
- 0 / 20 - 2500 pg/mL
- storage:
- 2 - 8 °C
- sensitivity:
- 12.4 pg/mL
- Species:
- Human
- Additional Info:
