ImmunoGuide® Enzyme immunoassay (ELISA) test kit for the determination of free antibodies directed against the drug Trastuzumab (Herceptin®, Herclon®) in serum and plasma.<br><br>
The drug Trastuzumab (trade names Herceptin®, Herclone®) is a recombinant DNA-derived humanized monoclonal antibody that selectively targets the extracellular domain of the human epidermal growth factor receptor 2 protein (HER2). The antibody is an IgG1 kappa that contains human framework regions with the complementarity-determining regions of a murine anti-p185 HER2 antibody that binds to HER2.<br><br>
According to the prescribing information, the use of Trastuzumab might be associated to the development of anti-Trastuzumab antibodies in various percentages of patients during therapy with the drug.<br><br>
The ImmunoGuide Antibody to Trastuzumab ELISA Kit can be efficiently used for monitoring Anti-Trastuzumab antibodies during therapy and offers the clinician a tool for decision on possible preventive measures. For research use only, not for use in diagnostic procedures.
- Assay Description:
- 1 hour incubation (RT) + 1 hour (RT) + 15 min. (RT) = 2 hours, 15 min. total incubation time
- Catalog number:
- TM09015
- configuration:
- 96 Determinations, 12x8 removable strips
- controls:
- Positive control
- design:
- Enzyme immunoassay (ELISA) technique
- FDA Status:
- For research use only, not for use in diagnostic procedures
- MSDS:
- Available upon request
- notes:
- The protocol for this product (see above) is intended to serve as an example only. Please refer to the Instructions For Use provided with the assay kit for precise details.
- Protocol:
- Sample types:
- Serum and plasma
- Sample volume:
- 10 µL
- Standards:
- 5 Standards, ready to use
- Standard range:
- 0 / 30 - 1000 ng/mL
- storage:
- 2 - 8 °C
- sensitivity:
- 30 ng/mL
- Species:
- Human
- Products related:
- Trastuzumab (Herceptin®) ELISA
Trastuzumab (Herceptin®) (mAb-based) ELISA - Additional info:
