Antibodies

An antibody is an immunoglobulin protein capable of specific combination with an antigen/hapten that has elicited and induced an immune response. Antibodies are produced by B cells in response to presence of antigen/hapten.

APP770 (351) Anti-Human Rabbit IgG Affinity Purify 1

Alzheimer's disease (AD) is a typical senile dementia and it is believed that accumulation of Amyloidβ (Aβ) in brain parenchyma is a major cause of the disease. Meanwhile, accumulation of Aβ has been also observed on cerebrovascular walls...

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Anti-Smad2L/3L (T220/T179 Phosphorylated) (1A1) Mouse IgG MoAb 1

Phosphorylation of signal transduction molecules, Smad2 and Smad3, can be an important information for understanding of various biological functions of transforming growth factor (TGF)-β. TGF-β type I receptor and cyclin-dependent kinases...

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Anti-Smad3L (Ser 208/213 Phosphorylated) Rabbit IgG Affinity Purify 1

Smads are critical mediators conveying signals from the TGF-β-superfamily members to the nucleus. Activated TGF-β type I receptor (TβRI) and c-Jun N-terminal kinase (JNK) differentially phosphorylate Smad3 to convert two distinctive...

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Septin 4 (C) Anti-Human Rabbit IgG Affinity Purify 1

A cytoskeletal or scaffold protein family named “septin” has been shown to be involved in diverse phenomena in the living body, including cell division. The term “septin” is derived from “septation,” which means...

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LGP2 Anti-Human Rabbit IgG Affinity Purify 1

A full-length cDNA encoding mouse LGP2 was cloned by computational analysis, RT-PCR, and RACE of liver and mammary tissue total RNA. And human LGP2 was also cloned. Yoneyama et al. have identified a DExD/H box-containing RNA helicase, retinoic acid...

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Girdin Anti-Human Rabbit IgG Affinity Purify 1

Girdin was discovered by a study group led by Takahashi as a new protein playing an important role in the infiltration and metastasis of cancer cells. It has been shown that Girdin, phosphorylated by the enzyme Akt/PKB within cancer cells, enhances the...

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c-Ret (R787) Anti-Human Rabbit IgG Affinity Purify 1

The ret proto-oncogene products (c-Ret) are expressed as 150kDa and 170kDaglycoproteins in neuroblastoma cells and as 150kDa and 190kDa glycoproteins in leukemia cells. These proteins are produced from a single polypeptide of 120kDa by posttranslational...

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CIS3/SOCS-3 (C204) Anti-Human Rabbit IgG Affinity Purify 1

The Janus family of protein tyrosine kinases (JAKs) and STAT transcription factors regulate cellular processes involved in cell growth, differentiation, and transformation through their association with cytokine receptors. The CIS family of proteins...

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CIS3/SOCS-3 (C005) Anti-Human Rabbit IgG Affinity Purify 1

The Janus family of protein tyrosine kinases (JAKs) and STAT transcription factors regulate cellular processes involved in cell growth, differentiation, and transformation through their association with cytokine receptors. The CIS family of proteins...

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CDCrel-1 (C354) Anti-Human Rabbit IgG Affinity Purify 1

Parkinson's Disease (PD) is a relatively common neurodegenerative disorder, which is characterized by the loss of midbrain dopamine (DA) neurons and the presence of Lewy bodies, proteinaceous cytoplasmic inclusions that are abundantly enriched in...

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CEA (1B2) Anti-Human Mouse IgG MoAb 2

The production of CEA is observed in many cancer tissues and the CEA value in the blood reflects tumor size. Therefore, the assay is widely used in a diagnosis and in monitoring of cancer.

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APP (N) (10D1) Anti-Human Mouse IgG MoAb 1

Amyloid precursor protein (APP) is precursor protein of Amyloid β which is major constituent of senile plaque in Alzheimer's disease. It is known that there are three major isoforms, APP695, APP751 and APP770, and are generated from alternative...

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